Staffan Strömblad Selected Research

1- (2- (1- (2- aminopyrimidin- 4- yl)- 2- ((2- methoxyethyl)amino)- 1H- 1,3- benzodiazol- 6- yl)ethynyl)cyclohexan- 1- ol

12/2015

p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells.

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Staffan Strömblad Research Topics

Disease

11	Neoplasms (Cancer) 01/2022 - 11/2004
6	Melanoma (Melanoma, Malignant) 01/2018 - 11/2004
3	Breast Neoplasms (Breast Cancer) 01/2020 - 09/2002
3	Prostatic Neoplasms (Prostate Cancer) 03/2013 - 12/2010
2	Neoplasm Metastasis (Metastasis) 01/2022 - 11/2010
1	Hypoxia (Hypoxemia) 01/2022
1	Progeria (Hutchinson Gilford Syndrome) 01/2021
1	Inflammation (Inflammations) 01/2018
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Body Weight (Weight, Body) 01/2017
1	Hypertrophy 06/2014
1	Neuroblastoma 03/2013
1	Ovarian Neoplasms (Ovarian Cancer) 10/2010
1	Carcinoma (Carcinomatosis) 09/2002
1	Retinal Neovascularization 04/2002

Drug/Important Bio-Agent (IBA)

6	IntegrinsIBA 01/2022 - 04/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2010
4	p21-Activated KinasesIBA 01/2021 - 10/2010
3	CollagenIBA 08/2012 - 11/2004
3	Integrin alphaVIBA 11/2004 - 04/2002
2	TalinIBA 01/2022 - 11/2012
2	Phosphotransferases (Kinase)IBA 05/2011 - 10/2010
2	Pharmaceutical PreparationsIBA 01/2011 - 12/2010
2	integrin alphaVbeta5IBA 07/2010 - 09/2002
1	prelamin AIBA 01/2021
1	CCAAT-Enhancer-Binding Protein-betaIBA 01/2020
1	Myosins (Myosin)IBA 01/2018
1	Myosin Type IIIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Tamoxifen FDA LinkGeneric 12/2015
1	1- (2- (1- (2- aminopyrimidin- 4- yl)- 2- ((2- methoxyethyl)amino)- 1H- 1,3- benzodiazol- 6- yl)ethynyl)cyclohexan- 1- olIBA 12/2015
1	Estrogen Receptor alphaIBA 12/2015
1	Transcription Factors (Transcription Factor)IBA 06/2014
1	cyclopamineIBA 03/2013
1	Protein Kinases (Protein Kinase)IBA 08/2012
1	Protein Kinase CIBA 08/2012
1	Monomeric GTP-Binding ProteinsIBA 05/2011
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 05/2011
1	Caspase 9IBA 01/2011
1	eprenetapoptIBA 01/2011
1	Cisplatin (Platino)FDA LinkGeneric 12/2010
1	Carrier Proteins (Binding Protein)IBA 11/2010
1	integrin-linked kinaseIBA 11/2010
1	Cyclin D1IBA 10/2010
1	ErbB Receptors (EGF Receptor)IBA 10/2010
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 10/2010
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2004
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 11/2004
1	RNA (Ribonucleic Acid)IBA 11/2004
1	VitronectinIBA 09/2002

Therapy/Procedure

3	Therapeutics 01/2021 - 10/2010
1	Radiotherapy 12/2011
1	Drug Therapy (Chemotherapy) 01/2011